Liquid Biopsy

Precision diagnosis and treatment in infectious diseases and cancer

Companies: UTE AMSlab and Nasasbiotech

The Andalusian Health Service (SAS) of the Ministry of Health and Families of the Andalusian Regional Government awarded these Galician biotechs one of the first Public Procurement of Innovation tender dossiers for the Precision Diagnosis and Treatment in Infectious Diseases and Cancer project, called Liquid Biopsy.

This solution aims to establish appropriate clinical guidelines on liquid biopsy analysis that enable the monitoring of patients, as well as the response to treatment in a personalised way, through 2 strategies:

• Lot 1: Obtaining and validation of a new diagnostic kit based on the detection and characterisation of circulating tumour DNA (ctDNA) through the LEVA Platform (LiquidBiopsy EV-ctDNAAnalysis), which integrates the purification of extracellular vesicles (EV), DNA extraction and mutation analysis.

• Lot 2: Obtaining and validation of a new diagnostic kit based on the detection and characterisation of circulating tumour cells (CTCs) through the ACTUA Platform (Analysis of Circulating Tumour Cells through an Automatic Unit), which integrates the isolation and characterisation of CTCs, the extraction and purification of their DNA, and the analysis of associated mutations, from peripheral blood samples.

The tendered file, Liquid Biopsy, with an execution period of 20 months, is part of the public procurement of innovation initiative, ‘Diagnosis and precision treatment in infectious diseases and cancer’, 80% co-financed with ERDF funds from the Programmes for the Promotion of Innovation from the Demand in Health (FID-SALUD), which is managed by the central government (Ministry of Science and Innovation) in collaboration with the communities, as well as with funds from the Andalusian Health Service.

Specifically, this project is supported by the Agreement signed on 4 December 2017 between the Ministry of Economy, Industry and Competitiveness (currently the Ministry of Science and Innovation) and the Andalusian Health Service.

Total budget: €6,040,784.00
ERDF co-financing: €4,832,627.20
Total budget of the awarded project: 674,338.84 €